34 Comments
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coords1306's avatar

This is epic . Skimmed through quickly. My intent will be to go back and actually click every single link along the way. I only knew of Boulware as the guy currently running a trial of dearly treatment drugs that included Ivermectin. It'll be interesting to read in detail his part in the HQC wars.

Mathew Crawford's avatar

Yes, I read your article and kept it in my notes. Thank you.

Alexander Ibid's avatar

Did you read any of my other stuff. I thought I did a good piece on early treatment on March 19th 2020 which was from an IT systems perspective. https://communityoperatingsystem.wordpress.com/2020/03/19/treat-covid-19-and-interstitial-pneumonia-early-at-home/

I also did a recent piece on how Pfizer's trial were impossible administrate and impossible to audit.

https://communityoperatingsystem.wordpress.com/2021/12/05/pfizers-rct-administrative-nightmare/

Mathew Crawford's avatar

I honestly don't know what I have and haven't read of your writing on the whole, but I will take a look at these links.

lymond's avatar

That was a fantastic read. Thanks!

coords1306's avatar

I thought he was a genuine actor and was optimistic his study of ivermectin would show some effect. They hadn't stopped it early. But from this portrayal I guess its safer to assume that the trial will somehow find a way to come short of statistical significance.

I've had this notion that it would just be a matter of time before the truth on early treatment would be allowed. Though apparently if it can be buried forever they'll try to bury it forever.

Mathew Crawford's avatar

The ivermectin study was a crap protocol. Designed to fail.

Alexander Ibid's avatar

If any given treatment led to a 10% fall in the severity of an illness then with things like flu and Covid that can be massively clinically significant in the numbers who end up hospitalized and dead. These RCTs are also useless for evaluating multi treatment protocols where agents are working together in synergy.

Barry O'Kenyan's avatar

Always keep the well-known adage about statistics.

Anyway, statistics are racist and bigoted!

WALTER GRAVES's avatar

Great stuff!!

Jay's avatar

Perhaps not relevant to this particular article but I'll ask here anyways:

When all cause mortality was "updated" in the phizer trial to 21vs17 placebo deaths, was that after the placebo arm was blown up and therefore not balanced cohorts anymore? Thanks

Mathew Crawford's avatar

Yes, the person-days spent in the arms started to diverge. They never shared the information for independent calculations to be done, but some envelope math says low or negative efficacy. The later updated numbers were even worse.

WALTER GRAVES's avatar

Please send to Dr. Raoult!!

WALTER GRAVES's avatar

Best analysis that you have ever done, Bravo, please send to Raoult!!

Mathew Crawford's avatar

I passed it along via an intermediary. I hope he will enjoy his appearance in the story.

WALTER GRAVES's avatar

After Raoult, I admire you the most, keep it up!!

Mathew Crawford's avatar

Now I have to find ways to be a better human being in order to deserve that.

WALTER GRAVES's avatar

I started following Dr. Raoult in March of 2020 and you have captured the essence of the good and the bad actors the best of anyone since then!!

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Dec 23, 2021
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BigT's avatar

Wonderful analogy. “Big Tony” lies and lies because he can. He single-handedly destroyed “science.”

Brian Mowrey's avatar

Until “Fake Vaccine Card,” “Fake Vaccine Passport,” and “Fake Vaccine Mandate” become official designations I will be using them in my imagination going forward

Susan J Carkin's avatar

Allen, get in contact with Steve Kirsch. He has a team of scientists ready to debate CDC et al.

J973's avatar

your graphs need titles and a better labeling. Especially the "Hydroxychloroquine Early Treatment and Pre Exposure ..." graph. People need to understand the graph quickly - otherwise they give up trying.

WALTER GRAVES's avatar

After Raoult I admire you the most!!

arthur brogard's avatar

'a body of evidence like this' - meaning that last chart? Well I might not have a brain because I completely fail to understand it. Any chance of an explanation?

Mathew Crawford's avatar

I added a link. Hopefully that will help.

arthur brogard's avatar

Ah... so each green bar represents a study.

Mathew Crawford's avatar

Correct. Red bars would too, but there were no studies to that point where the treatment group did worse for the most severe endpoint studied.

Gort@ControlGroup.Science's avatar

Hay Seuss Mathew, this is brilliant science, satire, and sport!